In S1E18, Lorelai is rambling jokingly about Richard’s mother being God. At the end of their conversation, in which Richard informs them that his mother is visiting, Lorelai says, “I just can’t get over that I’m related to God. That’s gonna make getting Madonna tickets so much easier.”
Madonna and her songs have already been referenced and discussed here, here, and here. Madonna Ciccone was born in 1958 and rose to fame in the 1980s. She is one of the best-selling musicians of all time.